Animal models of Neurobehavioral Disorders

The foundation of Animal Models is the notion that numerous animal species share behaviors or diseases with humans. Rodents, fruit flies, C. elegans worms, non-human primates, and other animals are used by scientists to study many facets of brain function and behavior. In all fields of biomedical research, Animal Models are essential. Despite the long history of utilizing animal models in the examination of Neuropsychiatric illnesses and behavioral dysfunctions, the process of animal model design, development, and evaluation has seldom been addressed in a systematic manner. The development and evaluation of animal models is proposed as an iterative, multi-stage process. The first step in the process is to decide what the model's purpose(s) will be, preferably based on theories regarding the connections between brain and behavior. The model is then created and put to the test. Scientific and moral standards are taken into account in the model's evaluation.

  • Disease induction models
  • Xenograft animal models
  • Inbred strains
  • Transgenic models

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